產(chǎn)品應(yīng)用
上海奧爾科特生物科技有限公司是研發(fā)、設(shè)計(jì)、制造科學(xué)實(shí)驗(yàn)儀器與系統(tǒng)設(shè)備的專業(yè)企業(yè),自1992年起致力于研發(fā)和生產(chǎn)生命科學(xué)實(shí)驗(yàn)系統(tǒng)與設(shè)備,產(chǎn)品廣泛應(yīng)用,為祖國(guó)的科學(xué)研究事業(yè)做出了貢獻(xiàn)。
奧爾科特公司產(chǎn)品為中國(guó)科學(xué)院、中國(guó)醫(yī)學(xué)科學(xué)院、軍事醫(yī)學(xué)科學(xué)院、北京大學(xué)、清華大學(xué)、復(fù)旦大學(xué)、上海交通大學(xué)、香港大學(xué)、阿斯利康、藥明康德等院校與企業(yè)采用。
奧爾科特公司產(chǎn)品被選用在國(guó)家高新技術(shù)研究發(fā)展項(xiàng)目、國(guó)家973計(jì)劃項(xiàng)目、國(guó)家863計(jì)劃項(xiàng)目、國(guó)家與軍隊(duì)重大計(jì)劃項(xiàng)目等各種重要科學(xué)研究,涵蓋醫(yī)學(xué)、藥物研發(fā)、化學(xué)、物理、生物、運(yùn)動(dòng)、心理、工業(yè)等領(lǐng)域。
在實(shí)驗(yàn)研究中使用奧爾科特的產(chǎn)品,近年發(fā)表的部分科學(xué)研究論著
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Captopril alleviates hypertension-induced renal damage, inflammation, and NF-κB activation,Brazilian Journal of Medical and Biological Research, 2018,vol.51 no.11
Schisandrin attenuates lipopolysaccharide-induced lung injury by regulating TLR-4 and Akt/FoxO1 signaling pathways, Front.Physiol.,08 August 2018
Hydrogen Inhalation is Superior to Mild Hypothermia for Improving Neurological Outcome and Survival in a Cardiac Arrest Model of Spontaneously Hypertensive Rat, Shock,December2018,Volume50,Issue6,p689-695
Erythropoietin alleviates post-resuscitation myocardial dysfunction in rats potentially through increasing the expression of angiotensin II receptor type 2 in ,Molecular Medicine Reports,2018 Volume17 Issue4
Rat Brainstem Hemorrhage Model: Key Points to Success in Modeling, World Neurosurgery,Volume 117, September 2018, Pages e106-e116
Proteomic analysis reveals the renoprotective effect of Tribulus terrestris against obesity-related glomerulopathy in rats, Biological and Pharmaceutical Bulletin, 2018Vol.41, No9 p1430-1439
BAPTA-AM Nanoparticle for the Curing of Acute Kidney Injury Induced by Ischemia/Reperfusion, Journal of Biomedical Nanotechnology, Volume 14, Number5, May2018,p868-883(16)
Astragaloside IV prevents obesity-associated hypertension by improving pro-inflammatory reaction and leptin resistance, Mol Cells. 2018 Mar 31; 41(3): 244–255.
Protective effects of low tidal volume mechanical ventilation associated with WISP1-TRL4 signaling pathway in a sepsis model of mice, Int J Clin Exp Med 2018;11(8):7872-7884
Overexpression of Arrestin1 in the Rostral Ventrolateral Medulla Downregulates Angiotensin Receptor and Lowers Blood Pressure in Hypertension. Front.Physiol.,28 March 2018
Combining early post-resuscitation EEG and HRV features improves the prognostic performance in cardiac arrest model of rats, The American Journal of Emergency Medicine.Volume 36, Issue 12, December 2018, Pages 2242-2248
Betaine Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats via Inhibiting Inflammatory Response, Molecules 2018, 23(6), 1274
Topotecan alleviates ventilator-induced lung injury via NF-κB pathway inhibition Cytokine,Volume 110, October 2018, Pages 381-388
Comparison of quantitative characteristics of early post-resuscitation EEG between asphyxial and ventricular fibrillation cardiac arrest in rats, Neurocritical Care,April 2018, Volume 28, Issue 2, pp 247-256
Synergism of amlodipine and candesartan on blood pressure reduction and organ protection in hypertensive rats, Clinical and Experimental Pharmacology and Physiology, Volume45, Issue6,June 2018, Pages 514-524
Antihypertensive effects, molecular docking study, and isothermal titration calorimetry assay of angiotensin I-converting enzyme inhibitory peptides from Chlorella, Journal of agricultural, 2018
With a new clip technique surgically inducing varicocele in Sprague-Dawley rats, BMC Urology,201818:58
LPS ameliorates renal ischemia/reperfusion injury via Hsp27 up-regulation, International Urology and Nephrology,March 2018, Volume 50, Issue 3, pp 571-580
Effects of small interfering RNA targeting TLR4 on expressions of adipocytokines in obstructive sleep apnea hyponea syndrome with hypertension in a rat model, Journal of cellular Physiology 2018 Volume233, Issue10,Pages 6613-6620
Protective cerebrovascular effects of hydroxysafflor yellow A (HSYA) on ischemic stroke,European Journal of Pharmacology, Volume 818, 5 January 2018, Pages 604-609
A1AR-mediated renal protection against ischemia/reperfusion injury is dependent on HSP27 induction,International Urology and Nephrology, July 2018, Volume 50, Issue 7, pp 1355–1363
Spatial receptive field shift by preceding cross‐modal stimulation in the cat superior colliculus,The Journal of Physiology, Volume596, Issue2015 Pages 5033-5050, 2018
Exosomes derived from human umbilical cord mesenchymal stem cells improve myocardial repair via upregulation of Smad7, International Journal of Molecular Medicine,2018,Volume 41 Issue 5
Dihydromyricetin improves vascular hyporesponsiveness in experimental sepsis via attenuating the over-excited MaxiK and KATP channels, Pharmaceutical Biology Volume 56, 2018-Issue 1
Comparative Study of Ocular Pharmacokinetics of Gatifloxacin Between Continuous Lavage and Hourly Topical Instillation in Rabbits,November 2018 Volume37,Issue11,p1457-1462
Huangqi (astragalus) decoction ameliorates diabetic nephropathy via IRS1-PI3K-GLUT signaling pathway, American journal Translational Research. 2018;10(8):2491-2501.
The Metabolomics Study of the Shexiang Baoxin Pill, Systems Biology and its Application in TCM Formulas Research,2018,Pages229-253
Therapeutic effects of acupuncture treatment on experimental rats with intracerebral hemorrhage via promoting neovascularization, Int J Clin Exp Med 2018;11(12):13235-13242
ALDH2 Protects Against Ischemic Stroke in Rats by Facilitating 4-HNE Clearance and AQP4 Down-Regulation, Neurochemical Research, July 2018, Volume 43, Issue7, p1339-1347
Identification and characterization of circular RNAs in rapid atrial pacing dog atrial tissue, Biochemical and Biophysical Research Communications, Volume 506, Issue 1, 17 November 2018, Pages 1-6
Ivabradine promotes angiogenesis and reduces cardiac hypertrophy in mice with myocardial infarction, Anatolian journal of cardiology, 2018 Nov; 20(5): 266–272
Effects of gene knockdown of CNP on ventricular remodeling after myocardial ischemia-reperfusion injury through NPRB/Cgmp signaling pathway in rats, Journal of cellular Biochemistry, Volume119, Issue2,February 2018,Pages 1804-1818
MicroRNA-210 promotes angiogenesis in acute myocardial infarction. Molecular Medicine Reports, 2018 Volume17 Issue4
Effect of acupuncture at three different acupoints on electrical activity of gastric distention-affected neurons in rat medial vestibular nucleus.Journal of Traditional Chinese Medicine Volume 38, Issue 1, February 2018, Pages 125-131
Effect of Sini decoction on angiotensin II, transforming growth factor β1 and connective tissue growth factor in rats with myocardial fibrosis-induced banding of the abdominal aorta.Journal of Traditional Chinese Medicine Volume 38, Issue 3, June 2018, Pages 427-432
Total Flavone of Rhododendron Improves Cerebral Ischemia Injury by Activating Vascular TRPV4 to Induce Endothelium-Derived Hyperpolarizing Factor-Mediated Responses. Evidence-Based Complementary and Alternative Medicine Volume 2018,
Lithium posttreatment alleviates blood–brain barrier injury after intracerebral hemorrhage in rats, NeuroscienceVolume 383, 15 July 2018, Pages 129-137
A potential role of Baicalin to inhibit apoptosis and protect against acute liver and kidney injury in rat preeclampsia model, Biomedicine & Pharmacotherapy, Volume 108, December 2018, Pages 1546-1552
Protective effects of PI3KCG gene on acute myocardial infarction, Journal of thoracic disease,2018 Feb; 10(2): 941–953
TGF-β1 and connexin-43 expression in neurogenic bladder from rats with sacral spinal cord injury, Neurourology and urodynamics, 2018 Volume37, Issue8,ages 2502-2509
Pharmacological postconditioning with Neuregulin-1 mimics the cardioprotective effects of ischaemic postconditioning via ErbB4-dependent activation of reperfusion injury salvage kinase pathway, Molecular Medicine2018,24:39
Ursolic acid ameliorates oxidative stress, inflammation and fibrosis in diabetic cardiomyopathy rats, Biomedicine & Pharmacotherapy, Volume 97, January 2018, Pages 1461-1467
A preventive injection of endothelial progenitor cells prolongs lifespan in stroke-prone spontaneously hypertensive rats, Clinical Science Aug 30, 2018
The contribution of different components in qishenyiqi pills to its potential to modulate energy metabolism in protection of ischemic myocardial injury,Frontiers in Physiology., 11April2018
Abnormalities in the fiber composition and contractility in diabetic skeletal muscles, Int J Clin Exp Med 2018;11(2):753-763
Role of miR-34c in the cognitive function of epileptic rats induced by pentylenetetrazol,Molecular Medicine Report,January 17, 2018,Pages: 4173-4180
Metabolic syndrome emerges after artificial selection for low baroreflex sensitivity,CNS neuroscience & Therapeutics, Volume24, Issue9 September 2018,Pages 828-836
Effects of mTOR/NF-κB signaling pathway and high thoracic epidural anesthesia on myocardial ischemia‐reperfusion injury via autophagy in rats,Volume233, Issue9,2018, Pages 6669-6678
Effects of Xin-Ji-Er-Kang on Anticardiovascular Remodeling in L-NAME Induced Hypertensive Mice and Its Potential Mechanisms,Evidence-Based Complementary and Alternative Medicine,Volume 2018,
Gualou xiebai decoction, a traditional chinese medicine, prevents cardiac reperfusion injury of hyperlipidemia rat via energy modulation,F(xiàn)rontiers in Physiology,04 April 2018
The protective effects of distal ischemic treatment on apoptosis and mitochondrial permeability in the hippocampus after cardiopulmonary resuscitation,Journal of cellular Physiology, 2018, Volume233, Issue9 Pages 6902-6910
Trimetazidine protects against myocardial ischemia/reperfusion injury by inhibiting excessive autophagy, Journal of Molecular Medicine,August 2018, Volume 96, Issue 8, pp 791–806
Intracerebroventricular injection of Aβ1-42 combined with two-vessel occlusion accelerate Alzheimer's disease development in rats,Pathology - Research and Practice,Volume 214, Issue 10, October 2018, Pages 1583-1595
Role of glutamine in the mediation of E-cadherin, p120-catenin and inflammation in ventilator-induced lung injury, Chinese medical J (Engl). 2018 Apr 5; 131(7): 804–812
Soluble epoxide hydrolase inhibition with t-TUCB alleviates liver fibrosis and portal pressure in carbon tetrachloride-induced cirrhosis in rats, Clinics and Research in Hepatology and Gastroenterology,2018 Volume 42, Issue 2,Pages e23-e38, 99-174
Rapid delivery of Hsa-miR-590-3p using targeted exosomes to treat acute myocardial infarction through regulation of the cell cyclem, Journal of Biomedical Nanotechnology, 2018,Volume14, Number5
扶正化瘀膠囊對(duì)心肌梗死大鼠心肌纖維化及TGF-β_1/Smads信號(hào)通路的影響.中西醫(yī)結(jié)合心腦血管病雜志,2018,16(09):1185-1189.
SK3表達(dá)在雌二醇介導(dǎo)的大鼠結(jié)腸平滑肌收縮中的作用.南京醫(yī)科大學(xué)學(xué)報(bào)(自然科學(xué)版),2018,38(06):753-757+815.
心室顫動(dòng)家兔QT變化與心肺復(fù)蘇后惡性心律失常的關(guān)系.廣西醫(yī)科大學(xué)學(xué)報(bào),2018,35(06):783-786.
人參總皂苷對(duì)大鼠急性心肌梗死模型血管新生及心功能的影響研究.中國(guó)畜牧獸醫(yī)文摘,2018,34(06):120-121.
奧普力農(nóng)調(diào)節(jié)自噬減輕大鼠心肌缺血-再灌注損傷.中華急診醫(yī)學(xué)雜志,2018,27(06):645-651.
生后不同間隔時(shí)間異氟烷處理對(duì)大鼠成年后認(rèn)知功能的影響.解放軍醫(yī)學(xué)雜志,2018,43(06):465-471.
預(yù)防性應(yīng)用辛伐他汀對(duì)大鼠腦出血后血腫體積和神經(jīng)功能的影響.中國(guó)臨床神經(jīng)外科雜志,2018,23(05):331-334
無血預(yù)充大鼠體外循環(huán)模型的建立.中國(guó)體外循環(huán)雜志,2018,16(03):184-188
大鼠心肌梗死后血管內(nèi)皮生長(zhǎng)抑制因子的時(shí)程變化.南京醫(yī)科大學(xué)學(xué)報(bào)(自然科學(xué)版),2018,38(05):612-615.
黃芪多糖對(duì)膿毒癥大鼠心臟功能及炎癥因子水平的影響.浙江中醫(yī)藥大學(xué)學(xué)報(bào),2018,42(05):354-359.
改良經(jīng)皮心外膜電刺激建立大鼠心臟驟停模型.中華急診醫(yī)學(xué)雜志,2018,27(05):513-517.
益氣活血方對(duì)心肌梗死大鼠心肌纖維化影響的研究.環(huán)球中醫(yī)藥,2018,11(05):670-675.
厚樸對(duì)胃腸動(dòng)力障礙作用的研究.中國(guó)醫(yī)藥導(dǎo)報(bào),2018,15(13):31-34.
基于腸外翻-離體血管聯(lián)用方法的銀丹心腦通軟膠囊血管活性評(píng)價(jià).中華中醫(yī)藥雜志,2018,33(05):1724-1729.
白芍總苷對(duì)心肌缺血再灌注大鼠內(nèi)質(zhì)網(wǎng)應(yīng)激因子CHOP、GRP78、GRP94的表達(dá)及凋亡的影響.現(xiàn)代生物醫(yī)學(xué)進(jìn)展,2018,18(08):1469-1473.
性別及去卵巢手術(shù)對(duì)腎血管性高血壓大鼠左心室肥厚的影響.新疆醫(yī)科大學(xué)學(xué)報(bào),2018,41(04):403-407.
芳香新塔花總黃酮對(duì)大鼠心肌缺血再灌注損傷的保護(hù)作用及機(jī)制.中國(guó)實(shí)驗(yàn)方劑學(xué)雜志,2018,24(14):115-121
大鼠陳舊性心肌梗死中碎裂QRS波與心力衰竭的關(guān)系研究.中國(guó)臨床保健雜志,2018,21(02):234-237.
腎血管性高血壓大鼠血管和腎臟組織中RSA組分蛋白表達(dá)的性別差異性研究.新疆醫(yī)科大學(xué)學(xué)報(bào),2018,41(04):408-413.
桂枝甘草湯對(duì)心力衰竭大鼠心肌凋亡及心肌細(xì)胞TGF-β1、ICAM-1表達(dá)的影響.中華中醫(yī)藥學(xué)刊,2018,36(04):932-935
蛋白激酶C和酪氨酸激酶在機(jī)械通氣相關(guān)肺損傷中的作用機(jī)制.中國(guó)醫(yī)藥,2018,13(04):537-540.
性別及年齡對(duì)原發(fā)性高血壓大鼠炎癥因子的影響.新疆醫(yī)科大學(xué)學(xué)報(bào),2018,41(04):399-402.
扶正化瘀膠囊對(duì)心肌梗死后心肌纖維化大鼠細(xì)胞外基質(zhì)代謝的影響.中醫(yī)雜志,2018,59(07):607-611.
柴胡龍骨牡蠣湯對(duì)心肌梗死大鼠骨髓c-kit~+干細(xì)胞動(dòng)員的影響.北京中醫(yī)藥大學(xué)學(xué)報(bào),2018,41(03):203-209.
妊娠對(duì)肺動(dòng)脈高壓肺循環(huán)影響的實(shí)驗(yàn)研究.心肺血管病雜志,2018,37(03):253-258.
性別對(duì)腎血管性高血壓大鼠血壓及靶器官損傷的影響.新疆醫(yī)科大學(xué)學(xué)報(bào),2018,41(04):389-393+398.
急性腹膜炎對(duì)大鼠羅庫(kù)溴銨腹肌松弛和腹直肌功能的影響.上海醫(yī)學(xué),2018,41(03):139-144.
銀杏內(nèi)酯注射液對(duì)腦缺血再灌注小鼠炎癥水平的影響.臨床醫(yī)藥文獻(xiàn)電子雜志,2018,5(76):1-5.
通心絡(luò)對(duì)豚鼠肥厚心肌電壓依賴性鉀通道的影響.中華老年心腦血管病雜志,2018,20(09):977-980.
骨橋蛋白在大鼠重度創(chuàng)傷性腦損傷后腸黏膜中表達(dá)水平變化.創(chuàng)傷與急危重病醫(yī)學(xué),2018,6(05):263-266.
參附注射液灌胃對(duì)MIRI模型大鼠Ca~(2+)、KATP通道的影響.臨床醫(yī)學(xué)研究與實(shí)踐,2018,3(26):5-6.
養(yǎng)陰潤(rùn)腸方改善慢傳輸型便秘模型ICC研究.中華中醫(yī)藥學(xué)刊,2018,36(09):2188-2191.
絲瓜絡(luò)不同炮制品治療功能失調(diào)性子宮出血的藥效比較.山東中醫(yī)雜志,2018,37(09):772-774.
17-甲氧基-7-羥基-苯駢呋喃查耳酮對(duì)小鼠心室肌細(xì)胞膜鈉電流的影響.中國(guó)現(xiàn)代應(yīng)用藥學(xué),2018,35(08):1185-1188.
神經(jīng)調(diào)節(jié)蛋白1/表皮生長(zhǎng)因子受體4信號(hào)通路的激活加強(qiáng)了七氟醚對(duì)心肌缺血/再灌注損傷大鼠的心肌保護(hù)作用.中國(guó)臨床藥理學(xué)雜志,2018,34(15):1843-1845.
滋陰潛陽方對(duì)2K1C高血壓大鼠腎損傷的影響.光明中醫(yī),2018,33(15):2181-2184.
七氟烷對(duì)大鼠肺缺血再灌注損傷中ATM的影響.中國(guó)老年學(xué)雜志,2018,38(15):3756-3759.
甘松揮發(fā)油對(duì)大鼠心肌缺血再灌注損傷及磷脂酰肌醇3激酶通路的影響.實(shí)用臨床醫(yī)藥雜志,2018,22(15):14-17.
通心絡(luò)對(duì)肥大細(xì)胞介導(dǎo)的大鼠心肌I/R損傷中β-氨基己糖苷酶、類糜蛋白酶及蛋白激酶C表達(dá)的影響.環(huán)球中醫(yī)藥,2018,11(08):1191-1195.
制川烏不同煎煮時(shí)間對(duì)心衰大鼠血流動(dòng)力學(xué)的影響.中國(guó)藥師,2018,21(08):1343-1347.
基于網(wǎng)絡(luò)藥理學(xué)構(gòu)建新型中藥復(fù)方降壓抗纖方抗高血壓心肌纖維化的作用.中國(guó)實(shí)驗(yàn)方劑學(xué)雜志,2018,24(20):115-122.
慢性情緒應(yīng)激對(duì)急性心肌梗死后骨髓c-kit~+干細(xì)胞動(dòng)員的影響.中國(guó)循環(huán)雜志,2018,33(07):709-713.
魚腥草揮發(fā)油對(duì)大鼠心肌缺血再灌注損傷的保護(hù)作用及機(jī)制研究.中南藥學(xué),2018,16(07):973-977.
PI3K/Akt信號(hào)通路在右美托咪定減輕體外循環(huán)大鼠肺缺血再灌注損傷的作用.中華麻醉學(xué)雜志,2018,38(07):803-807.
大鼠心肌缺血再灌注損傷模型線粒體自噬變化的研究.現(xiàn)代生物醫(yī)學(xué)進(jìn)展,2018,18(13):2452-2456.
黃芪甲苷聯(lián)合依那普利治療改善小鼠急性心肌梗死后心功能.南京醫(yī)科大學(xué)學(xué)報(bào)(自然科學(xué)版),2018,38(07):945-949+1000.
基于TLR4/NF-κB通路探討滋陰潛陽方對(duì)兩腎一夾高血壓大鼠腎損傷保護(hù)作用的機(jī)制.江西中醫(yī)藥大學(xué)學(xué)報(bào),2018,30(05):82-85.
銀杏內(nèi)酯注射液對(duì)腦缺血再灌注損傷治療時(shí)間窗及凋亡信號(hào)通路的影響.藥物評(píng)價(jià)研究,2018,41(07):1169-1173.
高壓氧預(yù)處理對(duì)大鼠腦出血后炎癥反應(yīng)的影響.健康研究,2018,38(03):294-297.
益氣活血顆粒對(duì)心肌梗死大鼠尿液代謝組學(xué)的影響.北京中醫(yī)藥大學(xué)學(xué)報(bào),2018,41(06):482-489.
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